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Epilepsy Clinical Trials in Florida
Open studies with at least one site in the state
Study listings come from ClinicalTrials.gov, where sponsors register and update their own studies. A listing does not mean a study is safe or effective, and DatenUS does not recommend any study. Talk with your doctor before joining a clinical trial, and use ClinicalTrials.gov for contact details and full eligibility rules.
- Open studies
- 29
- With a site in Florida
- Most studies in
- Miami
- 16 of the studies shown
Studies
29 of 29, recruiting studies first. Cities are where the study lists a Florida site.
- Diagnosing Epilepsy To EffeCT ChangeRecruitingNCT07110337· Epiminder America, Inc.
Jacksonville, Miami, Tampa
- Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1RecruitingPhase 3NCT07563881· Rapport Therapeutics Inc.
Gulf Breeze
- A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet SyndromeRecruitingPhase 1, Phase 2NCT05419492· Encoded Therapeutics
Miami
- Diagnosing Epilepsy To EffeCT Change Long-Term Follow-UpRecruitingNCT07110454· Epiminder America, Inc.
Jacksonville, Miami, Tampa
- Post-Market Real-World Evidence Registry for the NeuroOne OneRF® Ablation System for EpilepsyRecruitingNCT07546253· NeuroOne Medical Technologies Corporation
Miami
- Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal SeizuresRecruitingPhase 3NCT07594119· Rapport Therapeutics Inc.
Maitland, Miami
- An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut SyndromeRecruitingPhase 3NCT05066217· Epygenix
Orlando, Miami, Winter Park
- A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic SeizuresRecruitingPhase 3NCT05667142· Xenon Pharmaceuticals Inc.
Jacksonville, Miami, Orlando, Pensacola and 3 more
- A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)RecruitingPhase 3NCT05716100· Xenon Pharmaceuticals Inc.
Gulf Breeze, Jacksonville
- A Study to Evaluate the Safety and Efficacy of JZP926 Capsule for the Treatment of Juvenile Myoclonic EpilepsyRecruitingPhase 2, Phase 3NCT07723963· Jazz Pharmaceuticals
Tampa
- RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset SeizuresRecruitingPhase 2NCT06798896· Supernus Pharmaceuticals, Inc.
Miami, Gulf Breeze, Kissimmee, Orlando and 2 more
- Optimizing Therapy in Epilepsy Using Seizure Forecasts Via EEG and WearablesRecruitingEarly Phase 1NCT07012148· Mayo Clinic
Jacksonville
- A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet SyndromeRecruitingPhase 3NCT04462770· Epygenix
Kissimmee, Winter Park
- AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe EpilepsyRecruitingPhase 1, Phase 2NCT06063850· UniQure Biopharma B.V.
Jacksonville
- Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy PatientsRecruitingPhase 1NCT07051629· Suninflam Inc
DeLand, Tamarac, Weston
- Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))RecruitingPhase 3NCT05135091· Neurona Therapeutics
Miami
- AI-Based Mobile Intervention on Medication Non-Adherence and TransitionRecruitingNCT07445074· University of Central Florida
Orlando
- An Examination of Whether Infrared Light Therapy Can Reduce Stress in People With EpilepsyRecruitingNCT07509177· Cynthia Kerson
North Miami
- Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant EpilepsyRecruitingPhase 2NCT05518578· Supernus Pharmaceuticals, Inc.
Jacksonville, Miami
- Methylphenidate for the Treatment of Epilepsy-related Cognitive DeficitsRecruitingPhase 4NCT04419272· VA Office of Research and Development
Miami
- North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)RecruitingNCT01694940· Columbia University
Gainsville
- SPN-817 Open-Label Extension Study in Adults With Focal Onset SeizuresRecruitingPhase 2NCT07141329· Supernus Pharmaceuticals, Inc.
Port Charlotte
- Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and AdultsRecruitingPhase 3NCT05219617· SK Life Science, Inc.
Tampa, Jacksonville, Orlando, Wellington
- A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)Enrolling by invitationPhase 3NCT06908226· Longboard Pharmaceuticals
Tampa, Gulf Breeze, Miami, Orlando
- An Open-label Study of XEN1101 in EpilepsyEnrolling by invitationPhase 3NCT05718817· Xenon Pharmaceuticals Inc.
Jacksonville, Miami, Orlando, Pensacola and 2 more
- Clinical Trial of Vormatrigine in Adult Patients With EpilepsyEnrolling by invitationPhase 3NCT07287163· Praxis Precision Medicines
Miami, Miami Lakes, Naples
- 5-SENSE Score Validation StudyEnrolling by invitationNCT06138808· Duke University
Gainesville
- Long-term Safety and Tolerability of BHV-7000Enrolling by invitationPhase 2NCT06443463· Biohaven Therapeutics Ltd.
Miami, Orlando, Tampa, Boca Raton and 10 more
- Testing a Novel Dry Electrode Headset for Electroencephalography TelehealthEnrolling by invitationNCT05380921· VA Office of Research and Development
Miami
Other brain and nerves studies in Florida
Frequently asked questions
- Are there epilepsy clinical trials in Florida?
- Yes. 29 epilepsy studies on ClinicalTrials.gov list at least one site in Florida and are recruiting, about to recruit or enrolling by invitation, including sites in Miami, Jacksonville, Tampa.
- What does recruiting mean?
- Recruiting means the study is currently enrolling participants. Not yet recruiting means it has been registered but has not started enrolling. Enrolling by invitation means participants are selected by the study team rather than through open enrollment.
- How do I join a clinical trial?
- Read the full eligibility criteria and contact information on ClinicalTrials.gov, then talk with your doctor about whether a study may be right for you. The study team decides who can enroll.
Source: ClinicalTrials.gov, National Library of Medicine · Last updated 10/26/2026