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PTSD Clinical Trials
Studies with U.S. locations that are recruiting, about to recruit or enrolling by invitation
Study listings come from ClinicalTrials.gov, where sponsors register and update their own studies. A listing does not mean a study is safe or effective, and DatenUS does not recommend any study. Talk with your doctor before joining a clinical trial, and use ClinicalTrials.gov for contact details and full eligibility rules.
- Open studies
- 317
- With at least one U.S. site
- States with a site
- 46
- Most studies
- Texas
- 60 studies
Recently updated studies
50 of 317, recruiting studies first. Choose a state to see studies near you.
- Randomized Trial of Tele Vs. Clinic TF-CBT in Puerto RicoRecruitingNCT06332209· Medical University of South Carolina
1 U.S. site in 1 state
- Rehabilitation Through Virtual Immersion & Integrated Exposure for Mild Traumatic Brain Injury (ReVIVE for mTBI)RecruitingPhase 1NCT07890337· Johns Hopkins University
1 U.S. site in 1 state
- Psilocybin Intervention for Veterans Overcoming Treatment-Resistant DepressionRecruitingPhase 3NCT07226232· VA Office of Research and Development
5 U.S. sites in 4 states
- Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress DisorderRecruitingPhase 2, Phase 3NCT07570654· COMPASS Pathways
9 U.S. sites in 7 states
- Exercise and Emotional Learning in Posttraumatic Stress DisorderRecruitingNCT06127342· Christal L Badour
2 U.S. sites in 2 states
- OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment UnitRecruitingNCT05156112· VA Office of Research and Development
1 U.S. site in 1 state
- Mindfulness-based Psilocybin Therapy for PTSDRecruitingPhase 2NCT07104916· Anthony P King
1 U.S. site in 1 state
- Neuromodulation and Neurorehabilitation for mTBIRecruitingNCT03819608· Northwestern University
2 U.S. sites in 2 states
- Trauma BPE Prolonged Exposure Therapy for Injured Individuals Admitted to a Level I Trauma CenterRecruitingNCT06210711· Baylor Research Institute
3 U.S. sites in 2 states
- Suvorexant for Treatment of AUD and PTSDRecruitingPhase 2NCT06679062· Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
2 U.S. sites in 2 states
- The ED-AWARENESS-2 TrialRecruitingNCT05534243· Washington University School of Medicine
4 U.S. sites in 4 states
- K08 VR Fear ConditioningRecruitingNCT07216222· University of California, Los Angeles
1 U.S. site in 1 state
- Cognitive Control Training for Extinction in PTSDRecruitingNCT06629064· VA Office of Research and Development
1 U.S. site in 1 state
- Dose Optimization of MDMA-Assisted Therapy for PTSDRecruitingPhase 2NCT06418178· Bronx VA Medical Center
1 U.S. site in 1 state
- NightWare and Cardiovascular Health in Veterans With PTSDRecruitingNCT06419959· VA Office of Research and Development
1 U.S. site in 1 state
- Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)RecruitingNCT07523685· Acacia Clinics
1 U.S. site in 1 state
- Screening & TReatment fOr Perinatal WomeN With PTSD in Substance Use Care SettinGs in Arkansas (STRONG Moms)RecruitingNCT07759882· University of Arkansas
1 U.S. site in 1 state
- The Effects of Stellate Ganglion Block Sleep in U.S. Active Duty Service Members and Veterans Receiving Prolonged Exposure Therapy for PTSDRecruitingNCT07667309· The University of Texas Health Science Center at San Antonio
2 U.S. sites in 1 state
- Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental IllnessRecruitingNCT05491538· VA Office of Research and Development
1 U.S. site in 1 state
- Induction of Dreaming With EEG and Anesthesia for Post-traumatic Stress DisorderRecruitingPhase 2NCT06577636· Stanford University
1 U.S. site in 1 state
- Psilocybin-Assisted TherapyRecruitingPhase 2NCT07332143· Emory University
1 U.S. site in 1 state
- HBOT Effects on First Responders' Cognition and Well-BeingRecruitingPhase 2NCT07852728· Summit Hyperbarics and Wellness
1 U.S. site in 1 state
- RISE Versus Advocacy-based Enhanced Care as Usual for Patients Experiencing IPVRecruitingNCT06906302· Boston University
3 U.S. sites in 3 states
- Hyperbaric Oxygen Therapy for Veterans With TBI and PCS: A Biomarker StudyRecruitingPhase 2NCT07849465· Summit Hyperbarics and Wellness
1 U.S. site in 1 state
- Treatment for PTSD and TinnitusRecruitingNCT07106593· The University of Texas Health Science Center at San Antonio
1 U.S. site in 1 state
- Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1RecruitingNCT04916327· Virginia Commonwealth University
1 U.S. site in 1 state
- Integrated Health Care for PTSDRecruitingNCT07220681· Veterans Medical Research Foundation
5 U.S. sites in 5 states
- An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSDRecruitingPhase 3NCT07836647· Transcend Therapeutics
2 U.S. sites in 2 states
- Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion SymptomsRecruitingPhase 2, Phase 3NCT07071350· Virginia Commonwealth University
1 U.S. site in 1 state
- Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSDRecruitingNCT05380050· VA Office of Research and Development
1 U.S. site in 1 state
- Mobile Anger Reduction InterventionRecruitingNCT06094933· VA Office of Research and Development
1 U.S. site in 1 state
- Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient StudyRecruitingPhase 1NCT06335407· Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
1 U.S. site in 1 state
- Inflammatory Challenge and FearRecruitingPhase 1NCT06630884· University of California, San Francisco
1 U.S. site in 1 state
- Multifaceted Intervention to Restore Resilience and Overcome RiskRecruitingNCT06988787· Icahn School of Medicine at Mount Sinai
1 U.S. site in 1 state
- Safety and Efficacy of Cannabidiol (CBD) for Symptoms of PTSD in AdultsRecruitingPhase 2NCT05269459· University of Nebraska
1 U.S. site in 1 state
- Intensive Multi-Couple Therapy for PTSD Versus Relationship Education in Military CouplesRecruitingNCT06047691· Penn State University
1 U.S. site in 1 state
- An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)RecruitingPhase 3NCT07456696· Transcend Therapeutics
37 U.S. sites in 20 states
- Piloting Virtual Reality Environments to Treat PTSD in Healthcare WorkersRecruitingEarly Phase 1NCT04887116· Weill Medical College of Cornell University
1 U.S. site in 1 state
- Targeted Plasticity Therapy for PTSDRecruitingNCT06266364· The University of Texas at Dallas
3 U.S. sites in 1 state
- Cervical Plexus Hydrodissection With D5W Versus NS for Treatment-Resistant PTSDRecruitingPhase 4NCT07382596· Dr. Dean Reeves Clinic
4 U.S. sites in 3 states
- Focused Ultrasound for PTSD in VeteransRecruitingPhase 2NCT06820138· VA Office of Research and Development
1 U.S. site in 1 state
- Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related DistressRecruitingNCT07483333· Anthony Vesco
1 U.S. site in 1 state
- Efficacy of a Multi-level School Intervention for LGBTQ YouthRecruitingNCT05541406· Washington University School of Medicine
23 U.S. sites in 2 states
- Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their ChildrenRecruitingNCT06262178· New York University
3 U.S. sites in 1 state
- Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the CourseRecruitingNCT06957067· United States Department of Defense
4 U.S. sites in 4 states
- A Hybrid 1 Effectiveness-Implementation Trial of Partner-Assisted Prolonged Exposure for PTSDRecruitingNCT06990191· United States Department of Defense
4 U.S. sites in 4 states
- A Neurosensory Account of Anxiety and Stress (Study 2)RecruitingNCT07079839· The University of Texas Health Science Center, Houston
1 U.S. site in 1 state
- Testing a Scalable Model of Care to Improve Patients Access to Mental Health Services After Traumatic InjuryRecruitingNCT05497115· Medical University of South Carolina
1 U.S. site in 1 state
- MOCHA: Embedded Inpatient Mental Health Care for High-Risk Perinatal PatientsRecruitingNCT07540585· Indiana University
1 U.S. site in 1 state
- The PREVENT Resilience StudyRecruitingNCT07568145· Emory University
2 U.S. sites in 1 state
PTSD studies by state
Frequently asked questions
- How many ptsd clinical trials are recruiting?
- 317 ptsd studies on ClinicalTrials.gov have at least one U.S. site and are open or about to open, out of 27,256 open U.S. studies overall.
- Which states have the most ptsd trials?
- Texas (60), California (58), Massachusetts (32) have the most studies with a site in the state.
- What does recruiting mean?
- Recruiting means the study is currently enrolling participants. Not yet recruiting means it has been registered but has not started enrolling. Enrolling by invitation means participants are selected by the study team rather than through open enrollment.
- How do I join a clinical trial?
- Read the full eligibility criteria and contact information on ClinicalTrials.gov, then talk with your doctor about whether a study may be right for you. The study team decides who can enroll.
Source: ClinicalTrials.gov, National Library of Medicine · Last updated 10/26/2026