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Stroke Clinical Trials
Studies with U.S. locations that are recruiting, about to recruit or enrolling by invitation
Study listings come from ClinicalTrials.gov, where sponsors register and update their own studies. A listing does not mean a study is safe or effective, and DatenUS does not recommend any study. Talk with your doctor before joining a clinical trial, and use ClinicalTrials.gov for contact details and full eligibility rules.
- Open studies
- 420
- With at least one U.S. site
- States with a site
- 47
- Most studies
- California
- 78 studies
Recently updated studies
50 of 420, recruiting studies first. Choose a state to see studies near you.
- Natural History of Stroke: Cause and DevelopmentRecruitingNCT00009243· National Institute of Neurological Disorders and Stroke (NINDS)
3 U.S. sites in 2 states
- Xeomin® and Gait Related Mobility After StrokeRecruitingPhase 4NCT04908423· Wake Forest University Health Sciences
1 U.S. site in 1 state
- Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)RecruitingNCT06511934· Leigh R. Hochberg, MD, PhD.
1 U.S. site in 1 state
- Telerehabilitation In The Home After StrokeRecruitingNCT06682429· University of California, Los Angeles
27 U.S. sites in 14 states
- Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients With Large Vessel OCclusion in the Angiography SuiTeRecruitingNCT06825897· Santiago Ortega Gutierrez
15 U.S. sites in 9 states
- Implementing Transcranial Direct Current Stimulation in a Rehabilitation SettingRecruitingNCT07535788· Casa Colina Hospital and Centers for Healthcare
1 U.S. site in 1 state
- Stroke and Systemic Embolism Prevention in Adult Participants With Atrial FibrillationRecruitingPhase 3NCT07626411· Regeneron Pharmaceuticals
49 U.S. sites in 18 states
- Determine the Effect of Targeted High-definition Transcranial Direct Current Stimulation (tDCS) on Reducing Post-stroke Upper Limb Motor ImpairmentsRecruitingNCT05479006· Carle Foundation Hospital
1 U.S. site in 1 state
- Registry for CADASILRecruitingNCT05567744· University of Wisconsin, Madison
1 U.S. site in 1 state
- Thrombectomy Using Pulsed Aspiration for Reperfusion of Brain OcclusionsRecruitingNCT06029491· RapidPulse, Inc
18 U.S. sites in 14 states
- Neuromodulation-Enhanced Use of RObotic BALANCE Training to Improve Balance Function in Individuals With StrokeRecruitingNCT07113041· Kessler Foundation
1 U.S. site in 1 state
- Safety in Adult Participants With Atrial Fibrillation Who Are Treated With AnticoagulationRecruitingPhase 2NCT07175428· Regeneron Pharmaceuticals
43 U.S. sites in 16 states
- Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Exosome Intranasal Instillations for StrokeRecruitingPhase 1NCT05158101· The Foundation for Orthopaedics and Regenerative Medicine
1 U.S. site in 1 state
- Locomotor Function Following Transcutaneous Electrical Spinal Cord Stimulation in Individuals With Hemiplegic StrokeRecruitingNCT05167786· Shirley Ryan AbilityLab
1 U.S. site in 1 state
- Continuous Dual Aspiration Technique With Zoom System for StrokeRecruitingNCT07491952· Imperative Care, Inc.
25 U.S. sites in 16 states
- Strategy for Improving Stroke Treatment ResponseRecruitingPhase 2NCT05948566· Translational Sciences, Inc.
52 U.S. sites in 28 states
- Effect of Neuro20 Functional Electrical Stimulation Suit on Autonomic Function, Muscle Performance, and GaitRecruitingNCT07164846· Brooks Rehabilitation
2 U.S. sites in 1 state
- Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson DiseaseRecruitingPhase 2NCT06638944· University of Illinois at Urbana-Champaign
2 U.S. sites in 2 states
- Elite AF IDE Trial (Elite AF)RecruitingNCT07287436· Boston Scientific Corporation
2 U.S. sites in 2 states
- Overground Virtual Reality (VR) Gait Rehabilitation for StrokeRecruitingNCT07676578· Indiana University
1 U.S. site in 1 state
- FORWARD: Functional Outcomes in Real-World Treatment And Revascularization of Non-dominant and Distal M2 OcclusionsRecruitingNCT07749170· Penumbra Inc.
5 U.S. sites in 4 states
- Telerehabilitation for Post-Stroke Hand FunctionRecruitingNCT07792655· University of Michigan
1 U.S. site in 1 state
- The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial FibrillationRecruitingPhase 3NCT05836987· Johns Hopkins University
93 U.S. sites in 29 states
- Brain Stimulation Enhance Post-stroke Walking Survivors and Healthy AdultsRecruitingNCT06191549· The University of Texas Medical Branch, Galveston
1 U.S. site in 1 state
- Explore the Effects of Cortical Priming on Visuomotor Stepping Learning in Persons With Chronic StrokeRecruitingNCT06681207· The University of Texas Medical Branch, Galveston
1 U.S. site in 1 state
- Myofascial Dysfunction in Post Stroke Shoulder PainRecruitingPhase 2NCT06718413· Johns Hopkins University
1 U.S. site in 1 state
- Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is UnsuitableRecruitingPhase 3NCT07430956· Regeneron Pharmaceuticals
43 U.S. sites in 18 states
- Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)RecruitingPhase 2NCT06226805· Basking Biosciences, Inc.
15 U.S. sites in 9 states
- Efficacy of a Telehealth Delivered Group Lifestyle Balance for People Post Stroke (tGLB-CVA)RecruitingNCT06569121· Baylor Research Institute
1 U.S. site in 1 state
- The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial AneurysmsRecruitingNCT07143019· phenox Inc.
25 U.S. sites in 18 states
- Vivistim Registry for Paired VNS Therapy (GRASP)RecruitingNCT05301140· MicroTransponder Inc.
16 U.S. sites in 8 states
- Cognition and Imaging With TigertrieverRecruitingNCT05531461· Rapid Medical
6 U.S. sites in 4 states
- Cognitive Strategies for Optimizing Brain Health And Managing Transgenerational Vascular Risk Factors Post-StrokeRecruitingNCT06479174· University of New Mexico
1 U.S. site in 1 state
- Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)RecruitingNCT07521930· Johns Hopkins University
1 U.S. site in 1 state
- Tele-CE in Severe StrokeRecruitingNCT07652970· University of Illinois at Chicago
1 U.S. site in 1 state
- Natural History Study of CADASILRecruitingNCT05072483· National Heart, Lung, and Blood Institute (NHLBI)
1 U.S. site in 1 state
- EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following StrokeRecruitingNCT05628324· VA Office of Research and Development
1 U.S. site in 1 state
- A Comparison of Cyclic Manual Direct Aspiration Thrombectomy (Plunger Technique) vs. Static Manual Direct Aspiration Thrombectomy for Treatment of Acute Large Vessel Occlusion StrokeRecruitingNCT07231380· Vanderbilt University Medical Center
1 U.S. site in 1 state
- Influence of Brain Oscillation-Dependent TMS on Motor FunctionRecruitingNCT03288220· National Institute of Neurological Disorders and Stroke (NINDS)
1 U.S. site in 1 state
- Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular RiskRecruitingPhase 3NCT04774159· Population Health Research Institute
24 U.S. sites in 15 states
- Effect of Neural Constraints on Movement in StrokeRecruitingEarly Phase 1NCT06666673· Northwestern University
1 U.S. site in 1 state
- Improving Measurement and Treatment of Post-stroke NeglectRecruitingNCT03317860· VA Office of Research and Development
1 U.S. site in 1 state
- Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy TrialRecruitingPhase 3NCT05611242· Mercy Health Ohio
60 U.S. sites in 26 states
- Epidiolex Trial for Presymptomatic Treatment of Sturge-Weber SyndromeRecruitingPhase 2NCT07778810· Johns Hopkins University
1 U.S. site in 1 state
- MindEx: A Novel, Multifocal, Cognitive Brain-Machine Interface SystemRecruitingNCT05936619· Nader Pouratian
1 U.S. site in 1 state
- Intra-Arterial Magnesium Therapy After Mechanical Thrombectomy in Acute Ischemic StrokeRecruitingPhase 1NCT06956521· Baylor College of Medicine
1 U.S. site in 1 state
- A Pilot Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368, a FAAH/MAGL Inhibitor, in Participants With Post-Stroke Spasticity (The STIPS Study)RecruitingPhase 2NCT07704840· Alberto Esquenazi
1 U.S. site in 1 state
- Non-Invasive Monitoring Methods in Patients With Acute Brain InjuryRecruitingNCT06504238· Boston Medical Center
1 U.S. site in 1 state
- Brain Stimulation Effects on Post-Stroke Fatigue and AphasiaRecruitingNCT07151677· Syracuse University
2 U.S. sites in 2 states
- WE-TRUST (Workflow Optimization to Reduce Time to Endovascular Reperfusion for Ultra-fast Stroke Treatment)RecruitingNCT04701684· Philips Clinical & Medical Affairs Global
3 U.S. sites in 3 states
Stroke studies by state
Frequently asked questions
- How many stroke clinical trials are recruiting?
- 420 stroke studies on ClinicalTrials.gov have at least one U.S. site and are open or about to open, out of 27,256 open U.S. studies overall.
- Which states have the most stroke trials?
- California (78), Texas (72), New York (66) have the most studies with a site in the state.
- What does recruiting mean?
- Recruiting means the study is currently enrolling participants. Not yet recruiting means it has been registered but has not started enrolling. Enrolling by invitation means participants are selected by the study team rather than through open enrollment.
- How do I join a clinical trial?
- Read the full eligibility criteria and contact information on ClinicalTrials.gov, then talk with your doctor about whether a study may be right for you. The study team decides who can enroll.
Source: ClinicalTrials.gov, National Library of Medicine · Last updated 10/26/2026