What does recruiting mean?

Recruiting means the study is currently enrolling participants. Not yet recruiting means it has been registered but has not started enrolling. Enrolling by invitation means participants are selected by the study team rather than through open enrollment.

How do I join a clinical trial?

Read the full eligibility criteria and contact information on ClinicalTrials.gov, then talk with your doctor about whether a study may be right for you. The study team decides who can enroll.

Checked Oct 26, 2026

Trial-Ready Cohort-Down Syndrome (TRC-DS)

NCT04165109 on ClinicalTrials.gov

Study listings come from ClinicalTrials.gov, where sponsors register and update their own studies. A listing does not mean a study is safe or effective, and DatenUS does not recommend any study. Talk with your doctor before joining a clinical trial, and use ClinicalTrials.gov for contact details and full eligibility rules.

Status: Recruiting
Phase: Observational
Planned enrollment: 550; Participants, all sites
U.S. sites: 18; In 17 states

Study details

Conditions: Down Syndrome, Alzheimer Disease, Dementia
Sponsor: University of Southern California (University, hospital or other organization)
Ages: 25 to 55 years
Sex: All
Healthy volunteers: Not accepted
Start: 06/07/2021
Primary completion (expected): 12/31/2027
Last updated by sponsor: 05/18/2026

Full eligibility rules, contacts and site names: NCT04165109 on ClinicalTrials.gov

Where the study has sites

Cities with at least one listed U.S. site. Some sites may not be enrolling yet.

Arizona: Phoenix
California: Orange
Colorado: Aurora
Illinois: Park Ridge
Indiana: Indianapolis
Kansas: Kansas City
Kentucky: Lexington
Massachusetts: Boston
Missouri: St Louis
Nevada: Las Vegas
New York: Staten Island
Ohio: Beachwood, Cincinnati
Oregon: Portland
Pennsylvania: Pittsburgh
Tennessee: Nashville
Texas: San Antonio
Wisconsin: Madison

Frequently asked questions

What does recruiting mean?: Recruiting means the study is currently enrolling participants. Not yet recruiting means it has been registered but has not started enrolling. Enrolling by invitation means participants are selected by the study team rather than through open enrollment.
How do I join a clinical trial?: Read the full eligibility criteria and contact information on ClinicalTrials.gov, then talk with your doctor about whether a study may be right for you. The study team decides who can enroll.

Source: ClinicalTrials.gov, National Library of Medicine · Last updated 05/18/2026

Data sources

ClinicalTrials.gov APINational Library of Medicine

Data as of 05/18/2026

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Trial-Ready Cohort-Down Syndrome (TRC-DS)

Study details

Where the study has sites

More studies on the same topic

Frequently asked questions