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Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Participants 1 Year of Age and Older

NCT05844449 on ClinicalTrials.gov

Study listings come from ClinicalTrials.gov, where sponsors register and update their own studies. A listing does not mean a study is safe or effective, and DatenUS does not recommend any study. Talk with your doctor before joining a clinical trial, and use ClinicalTrials.gov for contact details and full eligibility rules.

Status
Enrolling by invitation
Phase
Phase 3
Interventional
Planned enrollment
174
Participants, all sites
U.S. sites
18
In 14 states

Study details

Conditions
Cystic Fibrosis
Sponsor
Vertex Pharmaceuticals Incorporated (Industry)
Ages
1 years and older
Sex
All
Healthy volunteers
Not accepted
Start
08/11/2023
Primary completion (expected)
07/30/2029
Last updated by sponsor
04/29/2026

Full eligibility rules, contacts and site names: NCT05844449 on ClinicalTrials.gov

Where the study has sites

Cities with at least one listed U.S. site. Some sites may not be enrolling yet.

  • California: Orange, Palo Alto
  • Colorado: Aurora
  • Georgia: Atlanta
  • Illinois: Chicago
  • Indiana: Indianapolis
  • Massachusetts: Boston
  • Minnesota: Minneapolis
  • Missouri: Kansas City, St Louis
  • New York: Lake Success
  • Ohio: Cincinnati, Cleveland, Columbus
  • Pennsylvania: Pittsburgh
  • Texas: Houston
  • Vermont: Colchester
  • Wisconsin: Madison

Frequently asked questions

What does recruiting mean?
Recruiting means the study is currently enrolling participants. Not yet recruiting means it has been registered but has not started enrolling. Enrolling by invitation means participants are selected by the study team rather than through open enrollment.
How do I join a clinical trial?
Read the full eligibility criteria and contact information on ClinicalTrials.gov, then talk with your doctor about whether a study may be right for you. The study team decides who can enroll.

Source: ClinicalTrials.gov, National Library of Medicine · Last updated 04/29/2026