Skip to content

Checked

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

NCT05877599 on ClinicalTrials.gov

Study listings come from ClinicalTrials.gov, where sponsors register and update their own studies. A listing does not mean a study is safe or effective, and DatenUS does not recommend any study. Talk with your doctor before joining a clinical trial, and use ClinicalTrials.gov for contact details and full eligibility rules.

Status
Recruiting
Phase
Phase 1
Interventional
Planned enrollment
45
Participants, all sites
U.S. sites
20
In 12 states

Study details

Conditions
Non-small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, Colorectal Carcinoma, Pancreatic Adenocarcinoma, Breast Cancer, Other Solid Tumors, Ovarian Cancer, Myeloid Neoplasms (AML/MDS)
Sponsor
AstraZeneca (Industry)
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Start
07/12/2023
Primary completion (expected)
07/31/2029
Last updated by sponsor
09/29/2026

Full eligibility rules, contacts and site names: NCT05877599 on ClinicalTrials.gov

Where the study has sites

Cities with at least one listed U.S. site. Some sites may not be enrolling yet.

  • Arizona: Gilbert
  • California: Duarte, Los Angeles, Newport Beach, Santa Monica
  • Florida: Jacksonville, Miami, Tampa
  • Massachusetts: Boston (2)
  • New Jersey: New Brunswick
  • New York: New York
  • North Carolina: Charlotte, Winston-Salem
  • Oregon: Portland
  • Pennsylvania: Pittsburgh
  • Tennessee: Nashville
  • Texas: Houston, Round Rock
  • Wisconsin: Milwaukee

More studies on the same topic

Frequently asked questions

What does recruiting mean?
Recruiting means the study is currently enrolling participants. Not yet recruiting means it has been registered but has not started enrolling. Enrolling by invitation means participants are selected by the study team rather than through open enrollment.
How do I join a clinical trial?
Read the full eligibility criteria and contact information on ClinicalTrials.gov, then talk with your doctor about whether a study may be right for you. The study team decides who can enroll.

Source: ClinicalTrials.gov, National Library of Medicine · Last updated 09/29/2026