Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

Conditions

Muscle Invasive Bladder Urothelial Carcinoma, Stage II Bladder Cancer AJCC v8, Stage IIIA Bladder Cancer AJCC v8

Sponsor

NRG Oncology (University, hospital or other organization)

Ages

18 years and older

Sex

All

Healthy volunteers

Not accepted

Start

10/07/2025

Primary completion (expected)

05/31/2030

Last updated by sponsor

10/23/2026

Full eligibility rules, contacts and site names: NCT07097142 on ClinicalTrials.gov

• Alaska: Fairbanks
• Arkansas: Fort Smith, Little Rock
• California: Los Angeles (3), Beverly Hills, Irvine, La Jolla, Orange, Sacramento, Tarzana, Torrance
• Colorado: Denver (2), Aurora, Highlands Ranch, Littleton, Lone Tree, Parker
• Delaware: Newark (3), Lewes, Millville, Rehoboth Beach, Wilmington
• Florida: Miami (3), Coral Gables, Deerfield Beach, Doral, North Miami, Plantation
• Georgia: Atlanta (4)
• Idaho: Coeur d'Alene, Post Falls
• Illinois: Peoria (4), Chicago (3), Springfield (3), Bloomington (2), Decatur (2), Effingham (2), O'Fallon (2), Peru (2), Alton, Canton, Carbondale, Carterville and 20 more
• Iowa: Des Moines (4), Clive (2), West Des Moines (2), Ankeny, Creston, Waukee
• Kansas: Garden City, Great Bend, Kansas City, Lawrence, Overland Park, Pittsburg, Topeka, Westwood, Wichita
• Kentucky: Lexington
• Louisiana: Baton Rouge (2), Metairie
• Massachusetts: Boston
• Michigan: Grand Rapids (3), Kalamazoo (3), Dearborn (2), Detroit (2), Farmington Hills (2), Saint Joseph (2), Ann Arbor, Battle Creek, Brighton, Brownstown, Clinton Township, Jackson and 11 more
• Minnesota: Coon Rapids (2), Edina (2), Maple Grove (2), Maplewood (2), Minneapolis (2), Saint Paul (2), Burnsville, Chaska, Monticello, Robbinsdale, Saint Cloud, Saint Louis Park and 5 more
• Missouri: St Louis (3), Cape Girardeau (2), Joplin (2), Kansas City (2), Rolla (2), Springfield (2), Bolivar, Columbia, Farmington, Lee's Summit, Osage Beach, Saint Joseph and 2 more
• Montana: Great Falls (2), Billings, Bozeman, Havre, Kalispell, Missoula
• Nevada: Reno
• New Hampshire: Lebanon
• New Jersey: Basking Ridge, Middletown, Montvale
• New York: New York (2), Rochester (2), Commack, Harrison, Uniondale, Webster
• North Carolina: Raleigh (2), Cary, Chapel Hill, Durham
• Ohio: Cleveland (2), Akron, Avon, Beachwood, Columbus, Mayfield Heights, Mentor, Strongsville
• Oklahoma: Oklahoma City (2)
• Pennsylvania: Chadds Ford, Danville, Dickson City, Hazleton, Hershey, Lewisburg, Wilkes-Barre
• South Carolina: Charleston, Gaffney, Greenwood, Greer, Spartanburg, Union
• Tennessee: Nashville (2)
• Texas: Dallas (2), Houston (2), Conroe, League City, Sugar Land, Temple
• Virginia: Richmond (2), Mechanicsville, Midlothian
• West Virginia: Morgantown, Parkersburg, Wheeling
• Wisconsin: Antigo, New Richmond, Rhinelander, Stevens Point, Wausau, Wisconsin Rapids
• Wyoming: Cheyenne

• Cancer (all types)

Frequently asked questions

What does recruiting mean?

Recruiting means the study is currently enrolling participants. Not yet recruiting means it has been registered but has not started enrolling. Enrolling by invitation means participants are selected by the study team rather than through open enrollment.

How do I join a clinical trial?

Read the full eligibility criteria and contact information on ClinicalTrials.gov, then talk with your doctor about whether a study may be right for you. The study team decides who can enroll.