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Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

NCT07157774 on ClinicalTrials.gov

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Status
Recruiting
Phase
Phase 3
Interventional
Planned enrollment
10,450
Participants, all sites
U.S. sites
159
In 35 states

Study details

Conditions
Elevated Lp(a), Atherosclerotic Cardiovascular Disease (ASCVD)
Sponsor
Eli Lilly and Company (Industry)
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Start
09/02/2025
Primary completion (expected)
March 2031
Last updated by sponsor
09/24/2026

Full eligibility rules, contacts and site names: NCT07157774 on ClinicalTrials.gov

Where the study has sites

Cities with at least one listed U.S. site. Some sites may not be enrolling yet.

  • Alabama: Birmingham
  • Arizona: Gilbert (2), Tucson (2), Apache Junction, Phoenix, Sun City West, Surprise
  • California: Beverly Hills, Concord, Escondido, Fountain Valley, Glendora, Huntington Beach, Inglewood, La Jolla, Redding, Santa Maria, Sherman Oaks, Torrance
  • Colorado: Aurora (2), Colorado Springs, Golden
  • Connecticut: Stamford, Waterbury
  • Florida: Boca Raton (2), Daytona Beach (2), Maitland (2), Miami (2), Cutler Bay, Hollywood, Jacksonville, Lady Lake, Lakeland, Miami Lakes, Naples, Ocala and 4 more
  • Georgia: Augusta (2), Gainesville, Johns Creek, Woodstock
  • Idaho: Blackfoot, Meridian, Rexburg
  • Illinois: Chicago, Gurnee, Lombard, Niles, Springfield
  • Indiana: Indianapolis (2), Bloomington
  • Iowa: West Des Moines
  • Kansas: Topeka
  • Kentucky: Covington
  • Louisiana: New Orleans
  • Maine: Scarborough
  • Maryland: Columbia (2), Baltimore, Beltsville, Bowie, Ft. Washington
  • Massachusetts: Boston, New Bedford, Quincy
  • Michigan: Dearborn, Troy
  • Montana: Missoula
  • Nevada: Las Vegas (2), Henderson, Reno, Sparks
  • New Jersey: Pennington, Somerset
  • New Mexico: Albuquerque (2)
  • New York: New York (2), Albany, East Syracuse, Rochester, Syracuse, West Seneca
  • North Carolina: Fayetteville, Greensboro, Monroe, Raleigh
  • Ohio: Cincinnati, Cleveland, Columbus
  • Oregon: Clackamas, Portland
  • Pennsylvania: Philadelphia (2), Allentown, Camp Hill, Duncansville, Horsham, Plymouth Meeting, Yardley
  • South Carolina: Charleston (2), Little River
  • South Dakota: Sioux Falls
  • Tennessee: Chattanooga (2), Jackson
  • Texas: Dallas (5), Houston (3), Austin (2), Fort Worth (2), McKinney (2), Amarillo, Duncanville, Lampasas, McAllen, Mesquite, Midland, Sherman
  • Utah: Ogden (2), Murray
  • Virginia: Manassas (2), Falls Church, Fredericksburg, Newport News, Norfolk, Reston, Richmond, Roanoke
  • Washington: Lynnwood, Redmond, Renton, Tacoma, Wenatchee
  • Wisconsin: Kenosha

Frequently asked questions

What does recruiting mean?
Recruiting means the study is currently enrolling participants. Not yet recruiting means it has been registered but has not started enrolling. Enrolling by invitation means participants are selected by the study team rather than through open enrollment.
How do I join a clinical trial?
Read the full eligibility criteria and contact information on ClinicalTrials.gov, then talk with your doctor about whether a study may be right for you. The study team decides who can enroll.

Source: ClinicalTrials.gov, National Library of Medicine · Last updated 09/24/2026