Skip to content

Checked

A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents

NCT07424404 on ClinicalTrials.gov

Study listings come from ClinicalTrials.gov, where sponsors register and update their own studies. A listing does not mean a study is safe or effective, and DatenUS does not recommend any study. Talk with your doctor before joining a clinical trial, and use ClinicalTrials.gov for contact details and full eligibility rules.

Status
Recruiting
Phase
Phase 3
Interventional
Planned enrollment
400
Participants, all sites
U.S. sites
56
In 22 states

Study details

Conditions
Schizophrenia, Autism-Related Irritability
Sponsor
Karuna Therapeutics, Inc., a Bristol Myers Squibb company (Industry)
Ages
5 to 17 years
Sex
All
Healthy volunteers
Not accepted
Start
04/07/2026
Primary completion (expected)
03/08/2030
Last updated by sponsor
10/15/2026

Full eligibility rules, contacts and site names: NCT07424404 on ClinicalTrials.gov

Where the study has sites

Cities with at least one listed U.S. site. Some sites may not be enrolling yet.

  • Alabama: Dothan
  • Arizona: Phoenix
  • California: Anaheim (2), Chino, Culver City, Glendale, Los Angeles, Orange, San Diego, San Francisco, San Rafael
  • Connecticut: New Haven
  • Florida: Gainesville (2), Boca Raton, Hollywood, Orlando
  • Georgia: Atlanta, Decatur, Lawrenceville, Stone Mountain
  • Illinois: Chicago (2)
  • Kentucky: Louisville
  • Massachusetts: Boston, Lexington, Worcester
  • Michigan: Bloomfield Hills
  • Missouri: Columbia, Saint Charles
  • Nebraska: Lincoln
  • Nevada: Las Vegas
  • New Jersey: Neptune City
  • New York: Great Neck, Orangeburg, Staten Island, The Bronx
  • Ohio: Cincinnati (2), West Chester
  • Pennsylvania: Danville, Pittsburgh
  • Tennessee: Nashville
  • Texas: Houston (2), Plano (2), Dallas, Garland, San Antonio, Spring
  • Utah: Orem, West Point
  • Virginia: Richmond
  • Washington: Everett

More studies on the same topic

Frequently asked questions

What does recruiting mean?
Recruiting means the study is currently enrolling participants. Not yet recruiting means it has been registered but has not started enrolling. Enrolling by invitation means participants are selected by the study team rather than through open enrollment.
How do I join a clinical trial?
Read the full eligibility criteria and contact information on ClinicalTrials.gov, then talk with your doctor about whether a study may be right for you. The study team decides who can enroll.

Source: ClinicalTrials.gov, National Library of Medicine · Last updated 10/15/2026