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Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA ≥ 0.2 ng/mL (EvoPAR-PR05)

NCT07711002 on ClinicalTrials.gov

Study listings come from ClinicalTrials.gov, where sponsors register and update their own studies. A listing does not mean a study is safe or effective, and DatenUS does not recommend any study. Talk with your doctor before joining a clinical trial, and use ClinicalTrials.gov for contact details and full eligibility rules.

Status
Recruiting
Phase
Phase 3
Interventional
Planned enrollment
1,330
Participants, all sites
U.S. sites
42
In 20 states

Study details

Conditions
Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
Sponsor
AstraZeneca (Industry)
Ages
18 years and older
Sex
Male only
Healthy volunteers
Not accepted
Start
09/15/2026
Primary completion (expected)
05/30/2031
Last updated by sponsor
10/15/2026

Full eligibility rules, contacts and site names: NCT07711002 on ClinicalTrials.gov

Where the study has sites

Cities with at least one listed U.S. site. Some sites may not be enrolling yet.

  • Arkansas: Hot Springs, Springdale
  • California: Beverly Hills, Los Alamitos, Los Angeles, San Diego
  • Florida: Margate, Miami, Orlando
  • Hawaii: Honolulu
  • Illinois: Chicago (2), Elk Grove Village, Hinsdale
  • Iowa: Ames
  • Maryland: Baltimore (2), Towson
  • Michigan: Detroit, Grand Rapids
  • Minnesota: Marshall
  • New Jersey: Camden
  • New Mexico: Albuquerque
  • New York: Shirley
  • Ohio: Canton, Cincinnati
  • Oregon: Portland (2)
  • South Carolina: Greenville
  • South Dakota: Aberdeen, Mitchell, Pierre, Sioux Falls, Yankton
  • Tennessee: Nashville
  • Texas: Austin, Dallas, Fort Worth, Longview, Wichita Falls
  • Utah: Salt Lake City
  • Washington: Spokane

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Frequently asked questions

What does recruiting mean?
Recruiting means the study is currently enrolling participants. Not yet recruiting means it has been registered but has not started enrolling. Enrolling by invitation means participants are selected by the study team rather than through open enrollment.
How do I join a clinical trial?
Read the full eligibility criteria and contact information on ClinicalTrials.gov, then talk with your doctor about whether a study may be right for you. The study team decides who can enroll.

Source: ClinicalTrials.gov, National Library of Medicine · Last updated 10/15/2026