Checked
Heart failure Clinical Trials in Florida
Open studies with at least one site in the state
Study listings come from ClinicalTrials.gov, where sponsors register and update their own studies. A listing does not mean a study is safe or effective, and DatenUS does not recommend any study. Talk with your doctor before joining a clinical trial, and use ClinicalTrials.gov for contact details and full eligibility rules.
- Open studies
- 62
- With a site in Florida
- Most studies in
- Jacksonville
- 22 of the studies shown
Studies
50 of 62, recruiting studies first. Cities are where the study lists a Florida site.
- Assessment of CCM in HF With Higher Ejection FractionRecruitingNCT05064709· Impulse Dynamics
Orlando, Cutler Bay, Miami, Weston
- A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)RecruitingPhase 2NCT06991257· Pfizer
Miami, Jacksonville, North Miami Beach, Pembroke Pines and 1 more
- Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With DapagliflozinRecruitingPhase 3NCT06677060· AstraZeneca
Miami, Boca Raton, Crystal River, Fort Lauderdale and 10 more
- Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart FailureRecruitingNCT07232030· CVRx, Inc.
Tampa, Clearwater, Jacksonville, Orlando and 1 more
- A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart DiseaseRecruitingNCT07214376· Pulnovo Medical, Inc.
Weston
- The WiSE®-UP Study (The WiSE System Utilization & Performance Study)RecruitingNCT07098858· EBR Systems, Inc.
Naples
- NORM-HF Pivotal StudyRecruitingNCT07574593· Foundry Innovation & Research 1, Limited (FIRE1)
Tampa, Jacksonville
- A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic DysfunctionRecruitingPhase 3NCT07188805· Bayer
Gainesville, Hollywood
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic DysfunctionRecruitingPhase 3NCT07192952· Bayer
Gainesville, Hollywood
- A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart FailureRecruitingPhase 3NCT06424288· Boehringer Ingelheim
Jacksonville, Naples, Ocala, Boca Raton and 14 more
- A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the HeartRecruitingPhase 3NCT06935370· Boehringer Ingelheim
Jacksonville, Miami, Brandon, Daytona Beach and 11 more
- Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney FunctionRecruitingPhase 3NCT06307652· AstraZeneca
Miami, Altamonte Springs, Boca Raton, Bradenton and 13 more
- Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection FractionRecruitingPhase 3NCT06736574· Cytokinetics
Clearwater, Fort Lauderdale, Hollywood, Jacksonville and 4 more
- INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac RecoveryRecruitingNCT06965504· Abiomed Inc.
Tampa
- A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)RecruitingPhase 2NCT07795814· Edgewise Therapeutics, Inc.
Gainesville
- CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)RecruitingNCT05996328· VA Office of Research and Development
Gainesville
- Alleviant ALLAY-HFrEF StudyRecruitingNCT06812533· Alleviant Medical, Inc.
Delray Beach, Pensacola, Tampa
- A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular HypertrophyRecruitingPhase 2NCT06979362· Novo Nordisk A/S
Miami Lakes, Orlando, Winter Park
- Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart FailureRecruitingNCT07069738· Boston Scientific Corporation
Sarasota, Tampa
- Early Feasibility Study - Edwards APTURE Transcatheter Shunt SystemRecruitingNCT03523416· Edwards Lifesciences
Jacksonville
- ELEVATE-HFpEF Clinical StudyRecruitingNCT06678841· Medtronic Cardiac Rhythm and Heart Failure
Panama City
- A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection FractionRecruitingPhase 1NCT07465653· Novartis Pharmaceuticals
Bradenton, Inverness, Jacksonville, Miami Lakes and 1 more
- A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEFRecruitingPhase 3NCT07761117· AstraZeneca
Miami, Miami Lakes, Bradenton, Hallandale and 7 more
- Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and ObesityRecruitingPhase 3NCT07037459· Amgen
Jacksonville, Orlando, Altamonte Springs, Aventura and 14 more
- A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure PatientsRecruitingPhase 3NCT06008197· Colorado Prevention Center
Miami, Bradenton, Brooksville, Fort Lauderdale and 5 more
- A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)RecruitingPhase 3NCT06024746· Colorado Prevention Center
Bradenton, Fort Lauderdale, Hialeah, Miami and 1 more
- Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart FailureRecruitingNCT06310031· BrioHealth Solutions, Inc.
Gainsville, Orlando
- Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)RecruitingPhase 2, Phase 3NCT05714085· Merck Sharp & Dohme LLC
St. Petersburg
- AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEFRecruitingPhase 2NCT06793371· Cytokinetics
Hialeah, Weston
- Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CMRecruitingNCT07690436· AstraZeneca
Jacksonville
- Diuretics Alone vs. Aortix Endovascular Device for Acute Heart FailureRecruitingNCT05677100· Procyrion
Tampa, Fort Lauderdale, Pensacola, Tallahassee and 1 more
- Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)RecruitingNCT04278404· Duke University
Jacksonville
- Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy ProductsRecruitingNCT00271180· Medtronic
Bradenton, Clearwater, Hollywood, Jacksonville and 4 more
- A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)RecruitingNCT05489705· Bristol-Myers Squibb
Jacksonville
- Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart FailureRecruitingNCT05650541· Analog Device, Inc.
Miami, Orlando
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and ObesityRecruitingPhase 3NCT07567001· Novo Nordisk A/S
Miami, Tampa, Clearwater, Coral Gables and 17 more
- Alleviant ALLAY-HF StudyRecruitingNCT05685303· Alleviant Medical, Inc.
Gainesville, Jacksonville, Naples, Orlando and 1 more
- TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast CancerRecruitingNCT05507879· Mayo Clinic
Gainesville, Jacksonville
- Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary HypertensionRecruitingPhase 1NCT06770023· Mayo Clinic
Jacksonville
- A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor AntagonistsRecruitingPhase 3NCT06033950· Colorado Prevention Center
Bradenton, Hialeah, Jacksonville, Miami and 1 more
- PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and IIIRecruitingNCT05934487· Endotronix, Inc.
Miami, Pensacola
- Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart FailureRecruitingNCT06526195· Abbott Medical Devices
Gainesville, Weston
- Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart FailureRecruitingPhase 4NCT06979726· University of Florida
Gainesville
- Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial HypercholesterolemiaRecruitingPhase 3NCT06597019· Novartis Pharmaceuticals
Boca Raton
- CCM OPEN HF RegistryRecruitingNCT07112924· Impulse Dynamics
Orlando, Tampa
- The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMRRecruitingNCT03142152· Cardiac Dimensions, Inc.
Miami, Delray Beach, Orlando, Palm Beach and 2 more
- Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart FailureRecruitingPhase 4NCT07263035· Lakeland Regional Health Systems, Inc.
Lakeland
- Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney DiseaseRecruitingPhase 3NCT06217302· Alessandro Doria
Orlando
- Utility of Thenar Near Infrared Spectroscopy (NIRS) in Pediatric Patients With Heart FailureRecruitingNCT02368041· University of Florida
Gainesville
- Observational Study Designed to Detect Decompensation of Congestive Heart Failure (dCHF) Using a Non-Invasive Wearable DeviceRecruitingNCT07350759· CHFDX,Inc.
Tampa
Other heart, blood and metabolism studies in Florida
Frequently asked questions
- Are there heart failure clinical trials in Florida?
- Yes. 62 heart failure studies on ClinicalTrials.gov list at least one site in Florida and are recruiting, about to recruit or enrolling by invitation, including sites in Jacksonville, Tampa, Miami.
- What does recruiting mean?
- Recruiting means the study is currently enrolling participants. Not yet recruiting means it has been registered but has not started enrolling. Enrolling by invitation means participants are selected by the study team rather than through open enrollment.
- How do I join a clinical trial?
- Read the full eligibility criteria and contact information on ClinicalTrials.gov, then talk with your doctor about whether a study may be right for you. The study team decides who can enroll.
Source: ClinicalTrials.gov, National Library of Medicine · Last updated 10/26/2026