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Federal dataScience & Research

PGS Catalog

Published by National Human Genome Research Institute

Last updated
Not listed
Update frequency
Not listed
Formats
Web only
Coverage
Nationwide
Federal data

About this dataset

The PGS Catalog is an open database of published polygenic scores (PGS). Each PGS in the Catalog is consistently annotated with relevant metadata; including scoring files (variants, effect alleles/weights), annotations of how the PGS was developed and applied, and evaluations of their predictive performance. PGS are identified via literature search and data is curated from eligible publications; direct submissions of scores and metadata can also be made. Software tools for working with the data are available including pgsc_calc: a reproducible workflow to calculate both PGS Catalog and custom polygenic scores, including multiple methods to normalise for genetic ancestry.

Files and access

Links open the official government source

Links open outside websites we do not control.

Frequently asked questions

Who publishes PGS Catalog?
National Human Genome Research Institute, part of U.S. Department of Health & Human Services, publishes this dataset on Data.gov.
How do I download it?
Use the official source link above to view or request the data.

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Where this catalog comes from

Catalog checked 10/24/2026

We list dataset descriptions only. Downloads and APIs link straight to the official government source, which holds the current version and its terms of use.

Source: Data.gov · Last updated 10/24/2026 · Listing only; the data stays with the publisher

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