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Alivio

lidocaine · Alivio is an amide local anesthetic (over-the-counter) containing lidocaine, made by Amerise Pharmaceuticals LLC.

Type
Over the counter
Drug class
Amide Local Anesthetic
Route
Transdermal
Manufacturers
1

Temporarily relieves minor pain

Drug facts

Generic name
lidocaine
Active ingredients
Lidocaine
Drug class
Amide Local AnestheticAntiarrhythmic
Dosage forms
Patch
Label holder
Amerise Pharmaceuticals LLC
FDA application
M017
Label updated
10/23/2025

Active ingredients

Lidocaine 4% .................................... Topical Anesthetic

Purpose

Temporarily relieves minor pain

Uses

Temporarily relieves minor pain

Directions

Adults and children over 12 years: clean and dry affected area remove backing from patch by firmly grasping both ends and gently pulling until back separates in middle use 1 patch for up to 12 hours Children 12 years or younger; ask a doctor

Warnings

For external use only. Do not use more than 1 patch on your body at a time or on cut, irritated or swollen skin on puncture wounds for more than one week without consulting a doctor When using this product use only as directed. Read and follow all directions and warning on this carton rare cases of serious burns have been reported with products of this type do not apply to wonds or damaged, broken or irritated skin do not allow contact with the eyes and mucous membranes do not bandage tightly or apply local heat (such as heating pads) to the area of use do not use at the same time as other topical analgesics dispose of used patch in manner that always keep product away from children and pets. Used patches still contain the drug product that can produce serious adverse effects if a child or pet chews or ingests this patch a transient buring sensation may occur upon applicaiton but generally disappears in several day if a severe buring sensation occurs, discontinue use immediately Stop use and ask a doctor if condition worsens redness is present irritation develops sypmtoms persist for more than 7 days or clear up and occur again within a few days you experience signs of skin injury, such as pain, swelling, or blistering where the product was applied. If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

And pets. If swallowed, get medical help or contact a Poison Control Center right away.

Inactive ingredients

Alpha-tocopherol acetate, aluminum hydroxide, aluminum silicate, butylated hydroxytoluene, butyl rubber, isoprene rubber, mineral oil, polyisobutylene, rosin, silicon dioxide, styrene/isoprene/styrene block, titanium dioxide

Forms and strengths

From the FDA NDC Directory · 1 product codes

Dosage formStrengthRouteNDCs
Patch4 gtransdermal1

Side effect reports to FDA

FDA Adverse Event Reporting System (FAERS), 57,975 reports that list lidocaine, data through 07/30/2026

Anyone can report a problem to FDA, and a report does not mean the drug caused the problem. Reports can be duplicated or incomplete, and counts depend on how widely a drug is used. Do not stop or change a medicine because of this list. Talk to your doctor or pharmacist.

Most often reported reactions

  • Drug ineffective4,341
  • Off label use4,128
  • Pain3,661
  • Fatigue3,499
  • Product adhesion issue3,452
  • Nausea3,399
  • Headache3,310
  • Product quality issue3,206
  • Sinusitis2,562
  • Dyspnea2,402

To report a side effect, use FDA MedWatch.

Manufacturers and labels

1 FDA label

  • Amerise Pharmaceuticals LLCShown hereM017 · Label 10/23/2025 · NDC 82598-101Full label

Related recalls

FDA drug recalls that name this drug or its active ingredient

All drug recalls

Alivio: common questions

What is Alivio used for?
Temporarily relieves minor pain
Is Alivio a prescription drug?
No. Alivio is sold over the counter (OTC) without a prescription.
Are there other products with the same active ingredient as Alivio?
Yes. Other FDA-listed products with the same active ingredients include Pain Relief Patches, Burn Relief, LIDOCAINE PAIN RELIEF Gel-Patch, Lidocaine Numbing Cream.
Who makes Alivio?
Amerise Pharmaceuticals LLC lists Alivio with the FDA.

Source: U.S. Food and Drug Administration, openFDA drug label (SPL) and NDC Directory · Last updated 10/23/2025 · Label text is shown as published by the manufacturer. Not medical advice