Is Hydrocortisone a prescription drug?

No. Hydrocortisone is sold over the counter (OTC) without a prescription.

Are there other products with the same active ingredient as Hydrocortisone?

Yes. Other FDA-listed products with the same active ingredients include CAREALL Hydrocortisone Maximum Strength, Hydrocortisone, Post-Treatment Repair Cream, Thompson Hydrocortisone 1%.

Who makes Hydrocortisone?

23 manufacturers list Hydrocortisone with the FDA, including Amazon.com Services LLC, A2A Integrated Pharmaceuticals, LLC, AKRON PHARMA INC.

Checked Oct 26, 2026

OTC

Hydrocortisone

Hydrocortisone is a corticosteroid (over-the-counter), made by 23 manufacturers.

Type: Over the counter
Drug class: Corticosteroid
Route: Topical
Manufacturers: 23; + 12 repackager labels

• temporarily relieves itching associated with minor skin irritations, rashes, and inflammation due to eczema • other uses of this product should be only under the advice and supervision of a doctor

Drug facts

Name: Hydrocortisone
Active ingredients: Hydrocortisone, Hydrocortisone Acetate
Drug class: Corticosteroid
How it works: Corticosteroid Hormone Receptor Agonists
Dosage forms: Cream, Lotion, Ointment
Label holder: Amazon.com Services LLC
FDA application: M017
Label updated: 08/25/2026

Active ingredients

Hydrocortisone 1%

Purpose

Anti-itch

Uses

Temporarily relieves itching associated with minor skin irritations, rashes, and inflammation due to eczema
Other uses of this product should be only under the advice and supervision of a doctor

Directions

Adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily
Children under 2 years of age: ask a doctor

Warnings

For external use only Do not use

For the treatment of diaper rash. Consult a doctor. When using this product
Avoid contact with eyes
Do not use more than directed unless told to do so by a doctor Stop use and ask a doctor if
Condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days, and do not begin use of any other hydrocortisone product unless you have asked a doctor Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. (1-800-222-1222)

Do not use

For the treatment of diaper rash. Consult a doctor.

Ask a doctor before use

Stop use and ask a doctor if

Condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days, and do not begin use of any other hydrocortisone product unless you have asked a doctor

When using this product

Avoid contact with eyes
Do not use more than directed unless told to do so by a doctor

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away. (1-800-222-1222)

Inactive ingredients

Aloe barbadensis leaf juice, avena sativa (oat) kernel extract, bisabolol, boswellia serrata gum, butyrospermum parkii (shea butter) extract, cetyl alcohol, dextrin, dimethicone, dipropylene glycol, edetate disodium, glycerin, glyceryl stearate, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane, magnesium ascorbyl phosphate, maltodextrin, methyl gluceth-20, methylparaben, petrolatum, phenoxyethanol, polysorbate 60, propylparaben, purified water, retinyl palmitate, sodium citrate, tocopheryl acetate, zingiber officinale (ginger) root extract

Questions?

1-800-719-9260

Forms and strengths

From the FDA NDC Directory · 46 product codes

Dosage form	Strength	Route	NDCs
Cream	.5 g/100g	topical	2
Cream	1 g/100g	topical	16
Cream	1 mg/100g	topical	1
Cream	10 mg/g	topical	13
Lotion	1 g/100g	topical	1
Lotion	1.14 g/114g	topical	1
Lotion	10 mg/mL	topical	1
Ointment	1 g/100g	topical	11

What pharmacies pay

National Average Drug Acquisition Cost (NADAC), week of 10/21/2026

All prices

Pharmacies paid about $0.0610 to $0.113 per gram across 5 package codes.

NADAC is a survey of what retail pharmacies pay to buy a drug. It is not the price you pay at the counter, which depends on your insurance and the pharmacy.

Side effect reports to FDA

FDA Adverse Event Reporting System (FAERS), 88,291 reports that list hydrocortisone, data through 07/30/2026

Anyone can report a problem to FDA, and a report does not mean the drug caused the problem. Reports can be duplicated or incomplete, and counts depend on how widely a drug is used. Do not stop or change a medicine because of this list. Talk to your doctor or pharmacist.

Most often reported reactions

Off label use11,929
Drug ineffective10,802
Fatigue9,272
Pain7,365
Nausea7,039
Condition aggravated6,989
Arthralgia6,954
Headache6,492
Rash6,469
Diarrhea6,383

To report a side effect, use FDA MedWatch.

Manufacturers and labels

47 FDA labels · 12 from repackagers

Amazon.com Services LLCShown hereM017 · Label 08/25/2026 · NDC 72288-469Full label
A2A Integrated Pharmaceuticals, LLCM017 · Label 03/31/2025 · NDC 73141-622Full label
AKRON PHARMA INCM017 · Label 07/22/2026 · NDC 71399-0120Full label
AKRON PHARMA INCM017 · Label 12/29/2025 · NDC 71399-0180Full label
ALLIED TRADE LINK LLCM017 · Label 11/12/2024 · NDC 84387-005Full label
Amazon.com Services LLCM017 · Label 08/12/2026 · NDC 72288-713Full label
CVS PHARMACY, INCM017 · Label 02/02/2026 · NDC 51316-230Full label
CVS PHARMACY, INCM017 · Label 10/07/2025 · NDC 51316-227Full label
Encube Ethicals, Inc.M017 · Label 11/10/2025 · NDC 21922-096Full label
H E BM017 · Label 10/29/2024 · NDC 37808-319Full label
H E BM017 · Label 10/12/2024 · NDC 37808-471Full label
H E BM017 · Label 09/29/2024 · NDC 37808-973Full label
J&A Digital Inc.M017 · Label 12/10/2024 · NDC 82942-1003Full label
Kroger CompanyM017 · Label 11/12/2024 · NDC 30142-411Full label
Kroger CompanyM017 · Label 09/29/2024 · NDC 30142-973Full label
Medrock Pharmacy LLCM017 · Label 02/17/2026 · NDC 85402-001Full label
Mericon IndustriesM017 · Label 03/17/2026 · NDC 0394-0859Full label
Nantong Health & Beyond Hygienic Products Inc.M017 · Label 08/08/2024 · NDC 43473-049Full label
Padagis Israel Pharmaceuticals LtdM017 · Label 04/29/2026 · NDC 45802-438Full label
Padagis Israel Pharmaceuticals LtdM017 · Label 01/14/2026 · NDC 45802-276Full label
STRATEGIC SOURCING SERVICES LLCM017 · Label 07/21/2025 · NDC 70677-1214Full label
Safetec of America, Inc.M017 · Label 08/13/2026 · NDC 61010-5800Full label
SafewayM017 · Label 12/26/2024 · NDC 21130-449Full label
Sun Pharmaceutical Industries, Inc.M017 · Label 07/03/2025 · NDC 51672-2010Full label
Sun Pharmaceutical Industries, Inc.M017 · Label 05/27/2025 · NDC 51672-2018Full label
TRIFECTA PHARMACEUTICALS USA LLCM017 · Label 03/11/2024 · NDC 69396-149Full label
TRIFECTA PHARMACEUTICALS USA LLCM017 · Label 02/29/2024 · NDC 69396-003Full label
Unifirst First Aid CorporationM017 · Label 09/09/2025 · NDC 47682-933Full label
Unifirst First Aid CorporationM017 · Label 09/08/2025 · NDC 47682-211Full label
Unifirst First Aid CorporationM017 · Label 09/08/2025 · NDC 47682-397Full label

Repackager labels (12)

A-S Medication Solutions10/02/2024
Acme United Corporation11/12/2024
Bryant Ranch Prepack08/04/2026
Bryant Ranch Prepack03/18/2026
HF Acquisition Co LLC, DBA HealthFirst08/05/2025
NuCare Pharmaceuticals,Inc.07/21/2025
Preferred Pharmaceuticals Inc.05/11/2026
Proficient Rx LP02/01/2024
Proficient Rx LP02/01/2024
Proficient Rx LP02/01/2024
Sportpharm LLC02/23/2026
Sportpharm LLC02/06/2026

Related recalls

FDA drug recalls that name this drug or its active ingredient

All drug recalls

Hydrocortisone: common questions

What is Hydrocortisone used for?: • temporarily relieves itching associated with minor skin irritations, rashes, and inflammation due to eczema • other uses of this product should be only under the advice and supervision of a doctor
Is Hydrocortisone a prescription drug?: No. Hydrocortisone is sold over the counter (OTC) without a prescription.
Are there other products with the same active ingredient as Hydrocortisone?: Yes. Other FDA-listed products with the same active ingredients include CAREALL Hydrocortisone Maximum Strength, Hydrocortisone, Post-Treatment Repair Cream, Thompson Hydrocortisone 1%.
Who makes Hydrocortisone?: 23 manufacturers list Hydrocortisone with the FDA, including Amazon.com Services LLC, A2A Integrated Pharmaceuticals, LLC, AKRON PHARMA INC.

Source: U.S. Food and Drug Administration, openFDA drug label (SPL) and NDC Directory · Last updated 08/25/2026 · Label text is shown as published by the manufacturer. Not medical advice

Same active ingredients

Brands and other versions

Same drug class

Corticosteroid

All

Data sources

openFDA drug labels (SPL)U.S. Food and Drug Administration
NDC DirectoryDosage forms, strengths and packages
DailyMedFull labels from the National Library of Medicine

Data as of 08/25/2026

Do not rely on openFDA to make decisions regarding medical care. While FDA makes every effort to ensure that data is accurate, all results should be assumed unvalidated. This page is for information only and is not medical advice. Talk to your doctor or pharmacist before starting, stopping or changing any medicine.

Related health info

About this data

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