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Itch Eraser

diphenhydramine hcl · Itch Eraser is an over-the-counter drug containing diphenhydramine hcl, made by Tender Corporation d/b/a Adventure Ready Brands.

Type
Over the counter
Drug class
Not classified
Route
Topical
Manufacturers
1

For the temporary relief of pain and itching associated with, minor burns, sunburn,minor cuts, insects bites, minor skin irritations, rashes due to poison ivy, poison oak, and poison sumac

Drug facts

Generic name
diphenhydramine hcl
Active ingredients
Diphenhydramine Hydrochloride
Dosage forms
Spray
Label holder
Tender Corporation d/b/a Adventure Ready Brands
FDA application
M017
Label updated
11/18/2025

Active ingredients

Diphenhydramine HCl 2%

Purpose

Topical Analgesic

Uses

For the temporary relief of pain and itching associated with, minor burns, sunburn,minor cuts, insects bites, minor skin irritations, rashes due to poison ivy, poison oak, and poison sumac

Directions

Shake before use remove safety tab from spray head adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily. children under 2 years of age: consult a doctor

Warnings

For external use only Do not use on large areas of the body, with any other product containing diphenhydramine, even one taken by mouth Ask a doctor before use on chicken ox, measles when using this product avoid contact with eyes. Stop use and ask a doctor if condition worses, if symptoms persist for more than 7 days or clear up and occur again within a few days. Keep out of reach of children if swallowed, get medical help or contact poison control center right away.

Do not use

On large areas of the body, with any other product containing diphenhydramine, even one taken by mouth

Ask a doctor before use

On chicken ox, measles

When using this product

Avoid contact with eyes.

Stop use and ask a doctor

Condition worses, if symptoms persist for more than 7 days or clear up and occur again within a few days.

Keep out of reach of children

If swallowed, get medical help or contact poison control center right away.

Inactive ingredients

Glycerinm oat beta glucanm povidone, purified water, sd alcohol 40-2, sodium bicarbonate (baking soda), tea tree oil, vitamine e acetate, zinc acetate

Forms and strengths

From the FDA NDC Directory · 1 product codes

Dosage formStrengthRouteNDCs
Spray.51 g/25.5gtopical1

Side effect reports to FDA

FDA Adverse Event Reporting System (FAERS), 11,077 reports that list diphenhydramine hcl, data through 07/30/2026

Anyone can report a problem to FDA, and a report does not mean the drug caused the problem. Reports can be duplicated or incomplete, and counts depend on how widely a drug is used. Do not stop or change a medicine because of this list. Talk to your doctor or pharmacist.

Most often reported reactions

  • Completed suicide796
  • Death685
  • Fatigue650
  • Nausea629
  • Pain565
  • Dyspnea547
  • Diarrhea533
  • Headache508
  • Drug ineffective498
  • Infusion related reaction496

To report a side effect, use FDA MedWatch.

Manufacturers and labels

1 FDA label

  • Tender Corporation d/b/a Adventure Ready BrandsShown hereM017 · Label 11/18/2025 · NDC 44224-1114Full label

Related recalls

FDA drug recalls that name this drug or its active ingredient

All drug recalls

Itch Eraser: common questions

What is Itch Eraser used for?
For the temporary relief of pain and itching associated with, minor burns, sunburn,minor cuts, insects bites, minor skin irritations, rashes due to poison ivy, poison oak, and poison sumac
Is Itch Eraser a prescription drug?
No. Itch Eraser is sold over the counter (OTC) without a prescription.
Are there other products with the same active ingredient as Itch Eraser?
Yes. Other FDA-listed products with the same active ingredients include Allergy Relief, nighttime sleep aid, Allergy Relief, Sleep Aid.
Who makes Itch Eraser?
Tender Corporation d/b/an Adventure Ready Brands lists Itch Eraser with the FDA.

Source: U.S. Food and Drug Administration, openFDA drug label (SPL) and NDC Directory · Last updated 11/18/2025 · Label text is shown as published by the manufacturer. Not medical advice