Checked
Refresh Plus
carboxymethylcellulose sodium · Refresh Plus is an over-the-counter drug containing carboxymethylcellulose sodium, made by Allergan, Inc..
- Type
- Over the counter
- Drug class
- Not classified
- Route
- Ophthalmic
- Manufacturers
- 1
For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun.
Related recalls
FDA drug recalls that name this drug or its active ingredient
- Class IIDrugOngoing09/30/2026AvKare Carboxymethylcellulose Sodium Ophthalmic Solution 0.5%, Lubricant Eye Drops, Sterile, 0.5 FL OZ (15...Sterling Pharmaceutical Services LLC · 5 products · Lack of Assurance of Sterility
- Class IIDrugOngoing05/14/2025Carboxymethylcellulose Sodium Ophthalmic Gel 1%, Carboxymethlycellulose Sodium 1% Eye Lubricant, Lubricant...BRS Analytical Services, LLC · 2 products · cGMP deviations and lack of assurance of sterility.
- Class IIIDrugOngoing01/08/2025Carboxymethylcellulose Sodium Ophthalmic Solution 0.5% Moisturizing Lubricant Eye Drops, 0.5 FL OZ (15 mL)...AvKARE · LABELING: LABEL MIX-UP
- Class IDrugOngoing02/14/2024CVS Health brand Lubricant Eye Drops (Carboxymethylcellulose Sodium 0.5%), packaged in a) 0.5 FL OZ (15mL)...Kilitch Healthcare India Limited · 7 products · Non-Sterility
- Class IDrugOngoing11/29/2023LEADER brand Dry Eye Relief (Carboxymethylcellulose Sodium, 1%); 0.5 FL OZ (15 mL) dropper bottle...Cardinal Health Inc. · 3 products · Non-Sterility: FDA found insanitary conditions and positive...
Active ingredients
Carboxymethylcellulose sodium 0.5%
Purpose
Eye lubricant
Uses
For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation.
Directions
To open, TWIST AND PULL TAB TO REMOVE. Instill 1 or 2 drops in the affected eye(s) as needed and discard container. *Follow your eye doctor’s instructions if you are using this product after an eye surgery (e.g., LASIK) to relieve eye dryness and discomfort.
Warnings
For external use only. To avoid contamination, do not touch tip of container to any surface. Do not reuse. Once opened, discard. Do not touch unit-dose tip to eye. If solution changes color or becomes cloudy, do not use. Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Stop use and ask a doctor
You experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours.
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Inactive ingredients
Calcium chloride dihydrate; magnesium chloride hexahydrate; potassium chloride; purified water; sodium chloride; and sodium lactate. May contain hydrochloric acid and/or sodium hydroxide (to adjust pH).
Questions?
1.800. 678.1605 refresh eyedrops .com v2.0DFL0403 Phone icon
Forms and strengths
From the FDA NDC Directory · 1 product codes
| Dosage form | Strength | Route | NDCs |
|---|---|---|---|
| Solution/ drops | 5 mg/mL | ophthalmic | 1 |
What pharmacies pay
National Average Drug Acquisition Cost (NADAC), week of 10/28/2026
Pharmacies paid about $0.260 to $0.297 per tablet, capsule or unit across 3 package codes.
NADAC is a survey of what retail pharmacies pay to buy a drug. It is not the price you pay at the counter, which depends on your insurance and the pharmacy.
Manufacturers and labels
1 FDA label
- Allergan, Inc.Shown hereM018 · Label 06/28/2022 · NDC 0023-0403Full label
Refresh Plus: common questions
- What is Refresh Plus used for?
- For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun.
- Is Refresh Plus a prescription drug?
- No. Refresh Plus is sold over the counter (OTC) without a prescription.
- Are there other products with the same active ingredient as Refresh Plus?
- Yes. Other FDA-listed products with the same active ingredients include Lubricant Eye Drops, Equate Lubricant Eye Drops, Up and Up Dry Eye Relief Lubricant Eye Drops, Walgreens Lubricant Eye Drops.
- Who makes Refresh Plus?
- Allergan, Inc. lists Refresh Plus with the FDA.
Source: U.S. Food and Drug Administration, openFDA drug label (SPL) and NDC Directory · Last updated 06/28/2022 · Label text is shown as published by the manufacturer. Not medical advice