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Soothe

bismuth subsalicylate · Soothe is a bismuth (over-the-counter) containing bismuth subsalicylate, made by Walgreens.

Type
Over the counter
Drug class
Bismuth
Route
Oral
Manufacturers
1

relieves diarrhea travelers diarrhea upset stomach due to overindulgence in food and drink, including: heartburn gas indigestion nausea fullness belching

Related recalls

FDA drug recalls that name this drug or its active ingredient

All drug recalls

Active ingredients

(in each 30 mL dose) Bismuth subsalicylate 525 mg

Purpose

Upset stomach reliever/Antidiarrheal

Uses

Relieves diarrhea travelers diarrhea upset stomach due to overindulgence in food and drink, including: heartburn gas indigestion nausea fullness belching

Directions

ML = milliliter shake well before using measure only with dosing cup provided. Do not use any other dosing device. keep dosing cup with product adults and children 12 years and over 30 mL (1 dose) every 1/2 or 60 mL (2 doses) every hour as needed for diarrhea/traveler's diarrhea 30 mL (1 dose) every 1/2 hour as needed for overindulgence (upset stomach, heartburn, indigestion, nausea) do not exceed 8 doses (240 mL) in 24 hours use until diarrhea stops but not more than 2 days children under 12 years of age: ask a doctor drink plenty of clear fluids to help prevent dehydration caused by diarrhea

Warnings

Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy alert: Contains salicylate. Do not take if you are allergic to salicylates (including aspirin) taking other salicylate products Do not use if you have an ulcer a bleeding problem bloody or black stool Ask a doctor before use if you have fever mucus in the stool Ask a doctor or pharmacist before use if you are taking any drug for diabetes gout arthritis anticoagulation (thinning the blood) When using this product a temporary, but harmless, darkening of the stool and/or tongue may occur. Stop use and ask a doctor if symptoms get worse or last more than 2 days ringing in the ears or loss of hearing occurs diarrhea lasts more than 2 days If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of childen. In case of overdose, get medical help or contact a Posion Control Center right away. (1-800-222-1222)

Do not use

If you have an ulcer a bleeding problem bloody or black stool

Ask a doctor before use

Fever mucus in the stool

Ask a doctor or pharmacist before use

Taking any drug for diabetes gout arthritis anticoagulation (thinning the blood)

When using this product

A temporary, but harmless, darkening of the stool and/or tongue may occur.

Stop use and ask a doctor

Symptoms get worse or last more than 2 days ringing in the ears or loss of hearing occurs diarrhea lasts more than 2 days

Pregnancy or breastfeeding

Ask a health professional before use.

Keep out of reach of children

Keep out of reach of childen. In case of overdose, get medical help or contact a Posion Control Center right away. (1-800-222-1222)

Other information

Each 30 mL contains: sodium 11 mg each 30 mL contains: salicylate 206 mg low sodium keep tightly closed protect from freezing avoid excessive heat (over 104ºF or 40ºC)

Inactive ingredients

Benzoic acid, D&C red #22, D&C red #28, flavor, glycerin, purified water, sucralose, xanthan gum

Questions?

Call 1-877-753-3935 Monday-Friday 9AM-5PM EST

Forms and strengths

From the FDA NDC Directory · 2 product codes

Dosage formStrengthRouteNDCs
Liquid525 mg/30mLoral2

Manufacturers and labels

2 FDA labels

  • WalgreensShown hereM008 · Label 04/08/2026 · NDC 0363-0736Full label
  • WalgreensM008 · Label 07/25/2024 · NDC 0363-0073Full label

Soothe: common questions

What is Soothe used for?
relieves diarrhea travelers diarrhea upset stomach due to overindulgence in food and drink, including: heartburn gas indigestion nausea fullness belching
Is Soothe a prescription drug?
No. Soothe is sold over the counter (OTC) without a prescription.
Are there other products with the same active ingredient as Soothe?
Yes. Other FDA-listed products with the same active ingredients include Stomach Relief Regular Strength, Stomach Relief Ultra, Stomach Relief Maximum Strength, Bismuth Subsalicylate.
Who makes Soothe?
Walgreens lists Soothe with the FDA.

Source: U.S. Food and Drug Administration, openFDA drug label (SPL) and NDC Directory · Last updated 04/08/2026 · Label text is shown as published by the manufacturer. Not medical advice

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