Checked
Soothe
bismuth subsalicylate · Soothe is a bismuth (over-the-counter) containing bismuth subsalicylate, made by Walgreens.
- Type
- Over the counter
- Drug class
- Bismuth
- Route
- Oral
- Manufacturers
- 1
relieves diarrhea travelers diarrhea upset stomach due to overindulgence in food and drink, including: heartburn gas indigestion nausea fullness belching
Related recalls
FDA drug recalls that name this drug or its active ingredient
- Class IIDrugOngoing12/10/2025Wecare Calasoothe, Net wt. 4 oz (113 g), Manufactured for: Dynarex Corporation, 10 Glenshaw Street...Blossom Pharmaceuticals · cGMP deviations
- Class IIDrug08/21/2019Soothe&Cool Protect Moisture Guard Skin Protectant, 3.5 oz. (99 g), tube, Manufactured for Medline...US Pharmaceuticals Inc. · CGMP Deviations: Out of Specification results for either total...
- Class IIDrug04/17/2019Bismuth Subsalicylate Oral Suspension 262mg/15mL, unit dose cups, OTC, Rpkg. By.: Lohxa Worcester, MA, NDC...Lohxa LLC · Labeling: Incorrect or Missing Lot and/or Exp Date - the label...
- Class IIDrug02/13/2019Soothe & Cool Protect Moisture Guard Skin Protectant (petrolatum 59%),3.5 oz tubes, Manufactured in USA...US Pharmaceuticals Inc. · GMP Deviations: Out of specification results for Total Aerobic...
- Class IIDrug11/07/2018Snore Soother, Homeopathic Oral Spray, 1.38 fl. oz (41ml), Manufactured for Sprayology Gaithersburg. MD...Sprayology · CGMP Deviations: products manufactured by contract manufacturer...
Active ingredients
(in each 30 mL dose) Bismuth subsalicylate 525 mg
Purpose
Upset stomach reliever/Antidiarrheal
Uses
Relieves diarrhea travelers diarrhea upset stomach due to overindulgence in food and drink, including: heartburn gas indigestion nausea fullness belching
Directions
ML = milliliter shake well before using measure only with dosing cup provided. Do not use any other dosing device. keep dosing cup with product adults and children 12 years and over 30 mL (1 dose) every 1/2 or 60 mL (2 doses) every hour as needed for diarrhea/traveler's diarrhea 30 mL (1 dose) every 1/2 hour as needed for overindulgence (upset stomach, heartburn, indigestion, nausea) do not exceed 8 doses (240 mL) in 24 hours use until diarrhea stops but not more than 2 days children under 12 years of age: ask a doctor drink plenty of clear fluids to help prevent dehydration caused by diarrhea
Warnings
Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy alert: Contains salicylate. Do not take if you are allergic to salicylates (including aspirin) taking other salicylate products Do not use if you have an ulcer a bleeding problem bloody or black stool Ask a doctor before use if you have fever mucus in the stool Ask a doctor or pharmacist before use if you are taking any drug for diabetes gout arthritis anticoagulation (thinning the blood) When using this product a temporary, but harmless, darkening of the stool and/or tongue may occur. Stop use and ask a doctor if symptoms get worse or last more than 2 days ringing in the ears or loss of hearing occurs diarrhea lasts more than 2 days If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of childen. In case of overdose, get medical help or contact a Posion Control Center right away. (1-800-222-1222)
Do not use
If you have an ulcer a bleeding problem bloody or black stool
Ask a doctor before use
Fever mucus in the stool
Ask a doctor or pharmacist before use
Taking any drug for diabetes gout arthritis anticoagulation (thinning the blood)
When using this product
A temporary, but harmless, darkening of the stool and/or tongue may occur.
Stop use and ask a doctor
Symptoms get worse or last more than 2 days ringing in the ears or loss of hearing occurs diarrhea lasts more than 2 days
Pregnancy or breastfeeding
Ask a health professional before use.
Keep out of reach of children
Keep out of reach of childen. In case of overdose, get medical help or contact a Posion Control Center right away. (1-800-222-1222)
Other information
Each 30 mL contains: sodium 11 mg each 30 mL contains: salicylate 206 mg low sodium keep tightly closed protect from freezing avoid excessive heat (over 104ºF or 40ºC)
Inactive ingredients
Benzoic acid, D&C red #22, D&C red #28, flavor, glycerin, purified water, sucralose, xanthan gum
Questions?
Call 1-877-753-3935 Monday-Friday 9AM-5PM EST
Forms and strengths
From the FDA NDC Directory · 2 product codes
| Dosage form | Strength | Route | NDCs |
|---|---|---|---|
| Liquid | 525 mg/30mL | oral | 2 |
Manufacturers and labels
2 FDA labels
- WalgreensShown hereM008 · Label 04/08/2026 · NDC 0363-0736Full label
- WalgreensM008 · Label 07/25/2024 · NDC 0363-0073Full label
Soothe: common questions
- What is Soothe used for?
- relieves diarrhea travelers diarrhea upset stomach due to overindulgence in food and drink, including: heartburn gas indigestion nausea fullness belching
- Is Soothe a prescription drug?
- No. Soothe is sold over the counter (OTC) without a prescription.
- Are there other products with the same active ingredient as Soothe?
- Yes. Other FDA-listed products with the same active ingredients include Stomach Relief Regular Strength, Stomach Relief Ultra, Stomach Relief Maximum Strength, Bismuth Subsalicylate.
- Who makes Soothe?
- Walgreens lists Soothe with the FDA.
Source: U.S. Food and Drug Administration, openFDA drug label (SPL) and NDC Directory · Last updated 04/08/2026 · Label text is shown as published by the manufacturer. Not medical advice