What city is ZIP code 78591?

ZIP code 78591 is in Santa Anna, TX (Starr County).

What county is ZIP code 78591 in?

ZIP code 78591 is mostly in Starr County, Texas.

How many people live in ZIP code 78591?

About 158 people live in the 78591 ZIP Code Tabulation Area, based on American Community Survey 5-year estimates.

Checked Oct 26, 2026

ZIP Code 78591

Santa Anna, TX, Starr County

Population

158

Land area

175.5sq mi

People per sq mi

City

Santa Anna

ZIP 78591 and nearby ZIP codes

Full map

ZIP 78591 at a glance

ZIP 78591 (Santa Anna) is 99% less dense than Texas as a whole.

Local data for ZIP 78591

Counts from official public data

Post Offices1

Economy and federal money

Businesses, pandemic loans and political donations

Details

PPP loans

$276K

10 loans

Campaign donations

$4,483

78% D, 0% R, 2026 cycle

PPP loans in this ZIP

Environment and hazard risk

ZIP 78591, from FEMA, NOAA and EPA

Full report

Natural hazard risk

Relatively Moderate

Top: cold wave

Storm events since 1996

549

Countywide, mostly drought

Flood insurance policies

152

0.9% of homes, county

July high / Jan low

99° / 45°F

22.5 inches of rain a year

Hazards, floods and storm history Check a flood zone

Health statistics

Share of adults in ZIP 78591, CDC PLACES estimates

All 40 measures

Obesity

42.3%

U.S. 33.3% +9.0 pts

Diabetes

24.4%

U.S. 12.1% +12.3 pts

Smoking

12.0%

U.S. 12.8% -0.8 pts

Uninsured (18-64)

31.4%

U.S. 11.1% +20.3 pts

Frequently asked questions

What city is ZIP code 78591?: ZIP code 78591 is in Santa Anna, TX (Starr County).
What county is ZIP code 78591 in?: ZIP code 78591 is mostly in Starr County, Texas.
How many people live in ZIP code 78591?: About 158 people live in the 78591 ZIP Code Tabulation Area, based on American Community Survey 5-year estimates.

Source: U.S. Census Bureau (ZIP Code Tabulation Areas, American Community Survey) · Data as of 12/31/2023. ZIP Code Tabulation Areas closely match, but are not identical to, USPS ZIP code delivery areas.