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Santee, SC

Town in Orangeburg County, South Carolina. ZIP codes: 29142.

Population

1,076

Land area

2.5sq mi

People per sq mi

430

ZIP codes

1

Santee and its ZIP codes

Full map

Santee at a glance

  • Santee is about 2.4 times as dense as South Carolina as a whole.
  • The median household income is $46,667, 33% below the South Carolina median of $69,324.
  • A typical owner-occupied home is valued at $161,800 (38% below South Carolina) and median rent is $911 a month.

Local data for Santee, SC

Counts from official public data

Housing and community stats

Santee, SC, American Community Survey 2020-2024

Full profile

Median household income

$46,667

Poverty rate

28.3%

Median home value

$161,800

Median rent

$911/mo

Homeownership

65.1%

Bachelor's or higher

31.1%

Median age

47.4

Average commute

31.4 min

Largest reported origins and ancestries: Indian Americans (102), German Americans (31), Filipino Americans (20).

Home values and rentsIncome, education and commute

Economy and federal money

Jobs, pay, income and spending are for Orangeburg County. PPP loans are for Santee.

Details

Unemployment rate

5.7%

Aug 2026, -1.1 pts in a year

Average annual pay

$48,883

27,181 jobs, 2025

Income per person

$47,455

BEA, 2024

Federal spending

$672M

FY 2026, $7,973 per person

PPP loans

$7.3M

217 loans, 1,260 jobs reported

Orangeburg County economyFederal spendingPPP loans

How people get to work

Santee, SC, workers 16 and older. American Community Survey 5-year estimates

  • Drove alone73.6%
  • Carpooled12.5%
  • Public transit0.0%
  • Walked0.0%
  • Bicycle0.0%
  • Taxi, ride-hailing, motorcycle or other9.1%
  • Worked from home4.9%

Average one-way commute: 31.4 minutes for people who do not work from home.

Environment and hazard risk

Santee, SC, from FEMA, NOAA and EPA

Full report

Natural hazard risk

Relatively Moderate

Top: earthquake

Storm events since 1996

816

Countywide, mostly thunderstorm wind

Flood insurance policies

187

0.5% of homes, county

July high / Jan low

91° / 35°F

50.4 inches of rain a year

Hazards, floods and storm historyCheck a flood zone

Health statistics

Share of adults in Santee, SC, CDC PLACES estimates

All 40 measures

Obesity

42.6%

U.S. 33.3% +9.3 pts

Diabetes

22.8%

U.S. 12.1% +10.7 pts

Smoking

16.3%

U.S. 12.8% +3.5 pts

Uninsured (18-64)

14.1%

U.S. 11.1% +3.0 pts

ZIP codes in Santee

1 in or overlapping Santee. Population shown

·

Cities near Santee

NameDistanceLand area (sq mi)
VanceTown4.8 mi0.5
North SanteeCensus-designated place5.5 mi9.1
ElloreeTown6.1 mi1.1
EutawvilleTown10 mi1
Holly HillTown11 mi1.3
SummertonTown11 mi1.4
CameronTown14 mi3.1
BowmanTown15 mi1.2
WybooCensus-designated place17 mi15
PinewoodTown18 mi1.1
HarleyvilleTown19 mi1.1
PaxvilleTown19 mi1.1
Wilkinson HeightsCensus-designated place20 mi3
BrookdaleCensus-designated place20 mi3.6
St. GeorgeTown21 mi2.8
St. MatthewsTown21 mi1.9

Frequently asked questions

What county is Santee, SC in?
Santee is in Orangeburg County, South Carolina.
What ZIP codes are in Santee, SC?
ZIP codes in or overlapping Santee include 29142.
What is the population of Santee, SC?
About 1,076 people live in Santee, based on American Community Survey 5-year estimates.
What cities are near Santee?
Nearby places include Vance (4.8 mi), North Santee (5.5 mi), Elloree (6.1 mi), Eutawville (10 mi), Holly Hill (11 mi).

Source: U.S. Census Bureau (TIGER/Line boundaries, American Community Survey) · Data as of 12/31/2023